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Refractory anemia with excess of blasts 2 Save


ICD-10 code: D46.22

Disease category: D46.2: Refractory anemia with excess of blasts [RAEB]

Understanding Refractory Anemia with Excess of Blasts 2

Refractory Anemia with Excess of Blasts 2 (RAEB-2) is a subtype of myelodysplastic syndrome (MDS), a collection of disorders characterized by abnormal production and maturation of blood cells. RAEB-2 is considered an intermediate stage in the progression of MDS, where the bone marrow produces a higher number of immature blood cells called blasts.

RAEB-2 is diagnosed when the percentage of blasts in the bone marrow reaches 5-19%. This condition primarily affects older adults and is more prevalent in males. While the exact cause of RAEB-2 is unknown, certain risk factors such as exposure to radiation, certain chemicals, and previous chemotherapy treatments may increase the likelihood of developing this condition.

Individuals with RAEB-2 may experience symptoms such as fatigue, weakness, shortness of breath, frequent infections, easy bruising, and bleeding. However, it is important to note that the severity and presence of symptoms may vary among individuals.

Diagnosis and Prognosis

Diagnosing RAEB-2 involves a thorough examination of the patient's medical history, physical examination, blood tests, and a bone marrow biopsy. These tests help determine the presence of excess blasts and the severity of the condition.

Once diagnosed, the prognosis for RAEB-2 varies depending on several factors, including the percentage of blasts, the presence of certain genetic abnormalities, and the overall health of the patient. Some individuals with RAEB-2 may progress to acute myeloid leukemia (AML), a more aggressive form of blood cancer.

Management and Support

Managing RAEB-2 involves a multidisciplinary approach that aims to alleviate symptoms, improve quality of life, and monitor disease progression. Treatment options may include blood transfusions to manage anemia, antibiotics to prevent and treat infections, and medications to stimulate the production of healthy blood cells.

Furthermore, individuals with RAEB-2 can benefit from a supportive care plan that includes regular follow-up visits, nutritional support, and emotional support. Engaging with support groups and connecting with others facing similar challenges can also provide valuable insight and encouragement.

  1. Regular follow-up visits with healthcare professionals
  2. Ensuring a balanced diet and proper nutrition
  3. Seeking emotional support from friends, family, or support groups
  4. Understanding and managing potential complications
  5. Maintaining a healthy lifestyle and managing stress levels

In conclusion, RAEB-2 is a subtype of MDS characterized by an excess of blasts in the bone marrow. While treatment options were not

Treatment of Refractory anemia with excess of blasts 2:

Treatment Options for Refractory Anemia with Excess of Blasts 2

Refractory anemia with excess of blasts 2 (RAEB-2) is a type of myelodysplastic syndrome (MDS) characterized by the abnormal production of blood cells in the bone marrow. It is a serious condition that requires appropriate treatment to manage symptoms and improve quality of life. Here are some treatment options commonl...

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