Anaplastic large cell lymphoma, ALK-negative, lymph nodes of multiple sites Save
ICD-10 code: C84.78
Disease category: C84.7: Anaplastic large cell lymphoma, ALK-negative
What is ALK-Negative Anaplastic Large Cell Lymphoma (ALCL)?
Anaplastic large cell lymphoma (ALCL) is a rare type of non-Hodgkin's lymphoma, a type of cancer that affects the lymphatic system. ALK-negative ALCL is a subtype of ALCL in which the cells lack a particular protein, called anaplastic lymphoma kinase (ALK). It is usually more aggressive than other types of ALCL and is more likely to spread to other parts of the body.
When ALK-negative ALCL is present, it often affects lymph nodes in multiple sites of the body, including the chest, abdomen, and pelvis. In some cases, the cancer may also spread to other organs, such as the bone marrow, spleen, or brain. Symptoms of ALK-negative ALCL may include swollen lymph nodes, fever, night sweats, and weight loss.
Diagnosis of ALK-negative ALCL typically involves a physical examination, imaging tests, and a biopsy of the affected lymph nodes. A biopsy is a procedure in which a small sample of tissue is removed from the body and examined under a microscope. The sample can help determine if the cells are malignant and if they are ALK-negative.
What are the Risk Factors for ALK-Negative ALCL?
The exact cause of ALK-negative ALCL is unknown, but there are some risk factors associated with the disease. These include:
- Age: ALK-negative ALCL is more common in individuals between the ages of 20 and 40.
- Gender: ALK-negative ALCL is more common in men than women.
- Immune system: People with weakened immune systems, such as those with HIV/AIDS or organ transplant recipients, are at higher risk of developing ALK-negative ALCL.
- Exposure to certain chemicals: People who are exposed to certain chemicals, such as pesticides or solvents, may have an increased risk of developing ALK-negative ALCL.
It is important to note that not everyone with these risk factors will develop ALK-negative ALCL. Additionally, some people may develop ALK-negative ALCL without any known risk factors.
Conclusion
ALK-negative ALCL is a rare subtype of ALCL that affects the lymph nodes in multiple sites of the body. Risk factors for the disease include age, gender, weakened immune system,
Treatment of Anaplastic large cell lymphoma, ALK-negative, lymph nodes of multiple sites:
Treatment Options for Anaplastic Large Cell Lymphoma, ALK-Negative, Lymph Nodes of Multiple Sites
Anaplastic large cell lymphoma (ALCL) is a rare form of Non-Hodgkin’s lymphoma that is typically seen in children and young adults. ALCL, ALK-negative, lymph nodes of multiple sites is a more aggressive variant of the disease. Treatment of this form of lymphoma is mostly done with a co...
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