Anaplastic large cell lymphoma (ALCL) is a rare type of non-Hodgkin lymphoma that affects the immune system. It can occur in various parts of the body, including the lymph nodes, skin, and organs such as the spleen.
ALCL can be categorized into two types: ALK-positive and ALK-negative. ALK stands for anaplastic lymphoma kinase, a protein that can be produced by cancer cells in some cases of ALCL.
When ALCL affects the spleen, it is referred to as anaplastic large cell lymphoma, ALK-positive, spleen. This subtype accounts for a small percentage of all cases of ALCL.
ALCL, including the spleen subtype, can cause a range of symptoms. Some of the most common ones include:
Sometimes, ALCL can also cause skin lesions or lumps that can be seen or felt on the skin.
The exact causes of ALCL, including the spleen subtype, are not fully understood. However, there are some factors that may increase the risk of developing this type of cancer. These include:
It is important to note that having one or more of these risk factors does not necessarily mean that someone will develop ALCL.
If ALCL, spleen subtype, is suspected, a doctor will typically perform a number of tests to confirm the diagnosis. These may include:
Anaplastic Large Cell Lymphoma (ALCL) is a rare and aggressive type of non-Hodgkin lymphoma (NHL) that affects the immune system. ALK-positive ALCL is a subtype of ALCL that is caused by a genetic mutation known as anaplastic lymphoma kinase (ALK). It affects both adults and children, and the sym...
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