Anaplastic large cell lymphoma, ALK-positive, spleen digital illustration

Anaplastic large cell lymphoma, ALK-positive, spleen Save


ICD-10 code: C84.67

Disease category: C84.6: Anaplastic large cell lymphoma, ALK-positive

Anaplastic Large Cell Lymphoma, ALK-Positive, Spleen: What You Need to Know

Anaplastic large cell lymphoma (ALCL) is a rare type of non-Hodgkin lymphoma that affects the immune system. It can occur in various parts of the body, including the lymph nodes, skin, and organs such as the spleen.

ALCL can be categorized into two types: ALK-positive and ALK-negative. ALK stands for anaplastic lymphoma kinase, a protein that can be produced by cancer cells in some cases of ALCL.

When ALCL affects the spleen, it is referred to as anaplastic large cell lymphoma, ALK-positive, spleen. This subtype accounts for a small percentage of all cases of ALCL.

Symptoms of Anaplastic Large Cell Lymphoma, ALK-Positive, Spleen

ALCL, including the spleen subtype, can cause a range of symptoms. Some of the most common ones include:

  1. Swollen lymph nodes, spleen, or other organs
  2. Fever
  3. Night sweats
  4. Weight loss
  5. Fatigue
  6. Itching
  7. Unexplained pain or discomfort

Sometimes, ALCL can also cause skin lesions or lumps that can be seen or felt on the skin.

Causes and Risk Factors of Anaplastic Large Cell Lymphoma, ALK-Positive, Spleen

The exact causes of ALCL, including the spleen subtype, are not fully understood. However, there are some factors that may increase the risk of developing this type of cancer. These include:

  • Having a weakened immune system
  • Being exposed to certain chemicals or toxins
  • Having a family history of lymphoma or other cancers
  • Having certain genetic mutations

It is important to note that having one or more of these risk factors does not necessarily mean that someone will develop ALCL.

Diagnosis of Anaplastic Large Cell Lymphoma, ALK-Positive, Spleen

If ALCL, spleen subtype, is suspected, a doctor will typically perform a number of tests to confirm the diagnosis. These may include:

  • Physical exam and medical history
  • Blood tests
  • Imaging tests, such as X-rays, CT scans, or

    Treatment of Anaplastic large cell lymphoma, ALK-positive, spleen:

    Anaplastic Large Cell Lymphoma (ALK-Positive) Treatment Options for Spleen Involvement

    Anaplastic Large Cell Lymphoma (ALCL) is a rare and aggressive type of non-Hodgkin lymphoma (NHL) that affects the immune system. ALK-positive ALCL is a subtype of ALCL that is caused by a genetic mutation known as anaplastic lymphoma kinase (ALK). It affects both adults and children, and the sym...

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