Corneal deposits in metabolic disorders, bilateral Save

Corneal Deposits in Metabolic Disorders, Bilateral

Corneal deposits are abnormal accumulations of substances in the cornea, the clear front part of the eye that covers the iris and pupil. These deposits can be caused by various factors, including metabolic disorders.

Metabolic disorders are conditions that affect the body's ability to convert food into energy. Some of these disorders can cause substances to accumulate in the body, including the cornea. Bilateral corneal deposits, meaning deposits in both eyes, are a common symptom of some metabolic disorders.

There are several types of metabolic disorders that can cause bilateral corneal deposits. One of the most common types is Fabry disease, a rare genetic disorder that affects the breakdown of a fatty substance called globotriaosylceramide (Gb3). In Fabry disease, Gb3 accumulates in various tissues, including the cornea, leading to cloudiness and reduced vision.

Another type of metabolic disorder that can cause corneal deposits is mucopolysaccharidoses (MPS), a group of rare genetic disorders that affect the body's ability to break down certain sugars. In MPS, substances called glycosaminoglycans (GAGs) accumulate in various tissues, including the cornea, leading to cloudiness and reduced vision.

Bilateral corneal deposits can also be a symptom of other metabolic disorders, such as cystinosis, hyperoxaluria, and Wilson's disease.

1. Corneal deposits in metabolic disorders are often bilateral, affecting both eyes.
2. Fabry disease, mucopolysaccharidoses (MPS), cystinosis, hyperoxaluria, and Wilson's disease are some of the metabolic disorders that can cause corneal deposits.
3. Corneal deposits can lead to cloudiness and reduced vision.

If you have bilateral corneal deposits or other vision problems, it is important to see an eye doctor for a comprehensive eye exam. Your doctor can help determine the underlying cause of your symptoms and recommend appropriate treatment options, which may include management of the underlying metabolic disorder.