Subacute sclerosing panencephalitis digital illustration

Subacute sclerosing panencephalitis Save


ICD-10 code: A81.1

Disease category: A81.1: Subacute sclerosing panencephalitis

Understanding Subacute Sclerosing Panencephalitis (SSPE)

Subacute Sclerosing Panencephalitis (SSPE) is a rare, chronic, and degenerative neurological disorder that affects the central nervous system. It is caused by a persistent infection with the measles virus, which leads to progressive inflammation and destruction of brain tissue. SSPE primarily affects children and adolescents who had measles infection earlier in life, typically between the ages of 5 and 15.

Here are some important facts to know about SSPE:

  1. Symptoms: SSPE symptoms may take years to develop after the initial measles infection. Early signs include personality changes, memory loss, irritability, and declining school performance. As the disease progresses, patients may experience seizures, muscle stiffness, jerking movements, and even loss of vision or hearing.
  2. Diagnosis: Diagnosing SSPE can be challenging due to its rarity and the long gap between measles infection and symptom onset. A combination of clinical evaluations, medical history, and specialized tests, such as electroencephalography (EEG) and brain imaging, are used to confirm the diagnosis.
  3. Causes: SSPE occurs as a result of a faulty immune response to the measles virus. The virus remains in the brain in a latent form for many years, leading to chronic inflammation and progressive damage to brain cells. The reasons why some individuals develop SSPE after measles infection are still not fully understood.
  4. Treatment: There is currently no cure for SSPE. Treatment options aim to manage symptoms, alleviate discomfort, and slow down the disease progression. Medications may be prescribed to control seizures or reduce inflammation. Supportive care, including physical therapy and educational support, can help improve quality of life for patients.
  5. Prevention: The most effective way to prevent SSPE is through measles vaccination. Maintaining high vaccination rates within communities can help reduce the risk of measles outbreaks and subsequent SSPE cases. Vaccination not only protects individuals but also contributes to the overall eradication of measles.

SSPE is a devastating condition that significantly impacts the lives of those affected and their families. While treatment options are limited, ongoing research is focused on understanding the disease and finding potential interventions to improve outcomes. Raising awareness about SSPE and the importance of measles vaccination can play a vital role in preventing its occurrence and ensuring a healthier future for everyone.

Treatment of Subacute sclerosing panencephalitis:

Treatment Options for Subacute Sclerosing Panencephalitis

Subacute sclerosing panencephalitis (SSPE) is a rare and devastating neurological disorder caused by a persistent measles virus infection. It primarily affects children and young adults, leading to progressive deterioration of the brain and nervous system. While there is currently no cure for SSPE, several treatment options ...

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