Subcutaneous panniculitis-like T-cell lymphoma digital illustration

Subcutaneous panniculitis-like T-cell lymphoma Save


ICD-10 code: C86.3

Disease category: C86: Other specified types of T/NK-cell lymphoma

Understanding Subcutaneous Panniculitis-Like T-Cell Lymphoma

Subcutaneous Panniculitis-Like T-Cell Lymphoma (SPTCL) is a rare type of non-Hodgkin lymphoma (NHL) that affects the skin and subcutaneous fat. This type of lymphoma is characterized by the infiltration of abnormal T-cells into the subcutaneous tissue, leading to the formation of nodules and plaques.

SPTCL is a variant of primary cutaneous T-cell lymphoma (CTCL), which accounts for about 75% of all CTCL cases. However, unlike other types of CTCL that affect the epidermis, SPTCL affects the deeper layers of the skin, such as the subcutaneous fat layer.

SPTCL is more common in adults than children, and it affects both men and women equally. The exact cause of SPTCL is unknown, but it is believed to be related to a genetic mutation that causes the T-cells to become abnormal and uncontrollable.

  1. Symptoms of SPTCL
  2. The most common symptom of SPTCL is the appearance of nodules or plaques on the skin, which may be painful and tender to the touch. These nodules may be red or purple in color and may be accompanied by fever and fatigue. In some cases, SPTCL can also affect other organs, such as the liver, spleen, and bone marrow, leading to additional symptoms.

  3. Diagnosis of SPTCL
  4. The diagnosis of SPTCL is based on a combination of clinical and laboratory findings. A skin biopsy is usually performed to confirm the presence of abnormal T-cells in the subcutaneous tissue. Additional tests, such as blood tests and imaging studies, may be performed to determine the extent of the disease and whether it has spread to other organs.

  5. Treatment of SPTCL
  6. The treatment of SPTCL depends on the extent of the disease and the symptoms it causes. In some cases, observation and monitoring may be sufficient, while in others, chemotherapy, radiation therapy, or immunotherapy may be necessary. A combination of these treatments may also be used to achieve the best possible outcome.

Overall, SPTCL is a rare and complex type of lymphoma that requires careful diagnosis and management. If you suspect that you may have SPTCL or are experiencing any of the symptoms associated with this condition, it is important to seek medical attention as soon as possible.

Treatment of Subcutaneous panniculitis-like T-cell lymphoma:

Treatment Options for Subcutaneous Panniculitis-Like T-Cell Lymphoma

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare type of non-Hodgkin lymphoma that affects the fatty tissue under the skin. It can be difficult to diagnose and treat, but there are several options available to manage the disease.

  1. Chemotherapy: This is the most commo...

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